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Achilles Tendinitis

Achilles Tendinitis

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No brain, No pain!

No brain, No pain!

The above post is reprinted from materials provided by Manchester UniversityNote: Materials may be edited for content and length.

Scientists at The University of Manchester have shown for the first time that the numbers of opiate receptors in the brain increases to combat severe pain in arthritis sufferers.

Chronic pain — pain which lasts for more than six months — is a real problem for many people with approximately 46% of the UK population estimated to suffer from it (comprising 20% of consultations in general practice). However, some people seem to cope better than others with pain, and knowing more about how these coping mechanisms work might help to develop new ways of treating this distressing symptom.

It has been known for a long time that we have receptors in our brains that respond to natural painkilling opiates such as endorphins, but the researchers in Manchester have now shown that these receptors increase in number to help cope with long-term, severe pain.

By applying heat to the skin using a laser stimulator, Dr Christopher Brown and his colleagues showed that the more opiate receptors there are in the brain, the higher the ability to withstand the pain.

The study used Positron Emission Tomography (PET) imaging on 17 patients with arthritis and nine healthy controls to show the spread of the opioid receptors.

This suggests that the increase in opiate receptors in the brain is an adaptive response to chronic pain, allowing people to deal with it more easily.

Dr Brown said: “As far as we are aware, this is the first time that these changes have been associated with increased resilience to pain and shown to be adaptive.

“Although the mechanisms of these adaptive changes are unknown, if we can understand how we can enhance them, we may find ways of naturally increasing resilience to pain without the side effects associated with many pain killing drugs.”

Professor Anthony Jones is the director of the Manchester Pain Consortium which is focused on improving the understanding and treatment of chronic pain. He said: “This is very exciting because it changes the way we think about chronic pain.

“There is generally a rather negative and fatalistic view of chronic pain. This study shows that although the group as a whole are more physiologically vulnerable, the whole pain system is very flexible and that individuals can adaptively upregulate their resilience to pain.

“It may be that some simple interventions can further enhance this natural process, and designing smart molecules or simple non-drug interventions to do a similar thing is potentially attractive.”

Val Derbyshire, a patient with arthritis said: “As a patient who suffers chronic pain from osteoarthritis, I am extremely interested in this research. I feel I have developed coping mechanisms to deal with my pain over the years, yet still have to take opioid medication to relieve my symptoms.

“The fact that this medication has to be increased from time to time concerns me greatly, due to the addictive nature of these drugs. The notion of enhancing the natural opiates in the brain, such as endorphins, as a response to pain, seems to me to be infinitely preferable to long term medication with opiate drugs.

“Anything that can reduce reliance on strong medication must be worth pursuing.”

Professor of Cognitive Neuroscience at the University, Wael El-Deredy said: “Receptor imaging is challenging and requires the co-ordination of a large team to collect and analyse the images. We are very lucky to have this technique in Manchester. There are very few places in the world where this study could have been done.”

The paper, ‘Striatal opioid receptor availability is related to acute and chronic pain perception in arthritis: Does opioid adaptation increase resilience to chronic pain?’, featured in the journal Pain, published by Wolters Kluwer.


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fascinating articles

fascinating articles

Understanding pain requires understanding what pain MEANS to a person.

Our fund of knowledge is rapidly changing.

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Ultrasound Guided Injections

Ultrasound Guided Injections

Ultrasound guidance is revolutionizing pain medicine.

We are rapidly doing more procedures with this real-time video imaging tool.

Ultrasound Guided InjectionsUltrasound Guided InjectionsF3

 

Ultrasound is the newest method of image guidance, allowing the physician to see in real time the soft tissue of the body.

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IHOP DR MCROBERT POTTER

Education: Procedures

a. Neuromodulation

university/

i. University

1. 1 https://www.youtube.com/watch?v=UNZLlsJlExU

2. 2 https://www.youtube.com/watch?v=dMN1Wx8rfqE

3. 3 https://www.youtube.com/watch?v=a6sCefrCX2k

4. 4 https://www.youtube.com/watch?v=kB-iph6jWcI

5. 5 https://www.youtube.com/watch?v=GiYaCg5sdKM

b. Biologic Regenerative Medicine for Pain

ii. High Frequency- Nevro Senza HF-10 SCS

iii. Dorsal Root Ganglion (DRG) Stimulation SCS

iv. Traditional (Tonic) SCS Stimulation

v. Novel Waveforms (Burst, Chaos, Pink Noise, High Density) SCS

vi. Hybrid Stimulation SCS+PNS

vii. Peripheral Nerve Stimulation PNS

viii. Intro to Nevro SCS

i. Bone Marrow Aspirate (BMA)

ii. Platelet Rich Plasma Injection (PRP)

c. Facet Joint Nerve Block and Ablation

d. Genicular Nerve Ablation

e. Sacral Nerve Ablation

f. Intrathecal Pump Implant

g. Totalis Micro Invasive Laminotomy for Spinal Stenosis

h. MILD Micro Invasive Lumbar Decompression for Spinal Stenosis

i. Vertiflex Superion Interspinous Spacer

j. Facet Joint Cyst Rupture

k. Epidural Injections

i. “BONC” Bolus Only No Continuous

i. Transforaminal Steroid Injections

ii. PRP Epidural Injections

iii. Cervical “SAFE” approach Transforaminal

l. Sacroilliac Joint Injections

m. Discography

n. MRIs

o. How to Prepare for your visit

p. Role of Physical Therapy in Pain Management

2. Education: Syndromes

a. Sacroilliac Joint

b. Cervical Spine Anatomy

c. Thoracic Spine Anatomy

d. Lumbar Spine Anatomy

e. Degenerative Disc Disease

f. Facet Join Syndromes

g. Opioids

3. Testimonials

i. Discogram

i. Vertebral Discs

Education: Procedures

a. Neuromodulation

university/

i. University

1. 1 https://www.youtube.com/watch?v=UNZLlsJlExU

2. 2 https://www.youtube.com/watch?v=dMN1Wx8rfqE

3. 3 https://www.youtube.com/watch?v=a6sCefrCX2k

4. 4 https://www.youtube.com/watch?v=kB-iph6jWcI

5. 5 https://www.youtube.com/watch?v=GiYaCg5sdKM

b. Biologic Regenerative Medicine for Pain

ii. High Frequency- Nevro Senza HF-10 SCS

iii. Dorsal Root Ganglion (DRG) Stimulation SCS

iv. Traditional (Tonic) SCS Stimulation

v. Novel Waveforms (Burst, Chaos, Pink Noise, High Density) SCS

vi. Hybrid Stimulation SCS+PNS

vii. Peripheral Nerve Stimulation PNS

viii. Intro to Nevro SCS

i. Bone Marrow Aspirate (BMA)

ii. Platelet Rich Plasma Injection (PRP)

c. Facet Joint Nerve Block and Ablation

d. Genicular Nerve Ablation

e. Sacral Nerve Ablation

f. Intrathecal Pump Implant

g. Totalis Micro Invasive Laminotomy for Spinal Stenosis

h. MILD Micro Invasive Lumbar Decompression for Spinal Stenosis

i. Vertiflex Superion Interspinous Spacer

j. Facet Joint Cyst Rupture

k. Epidural Injections

i. “BONC” Bolus Only No Continuous

i. Transforaminal Steroid Injections

ii. PRP Epidural Injections

iii. Cervical “SAFE” approach Transforaminal

l. Sacroilliac Joint Injections

m. Discography

n. MRIs

o. How to Prepare for your visit

p. Role of Physical Therapy in Pain Management

2. Education: Syndromes

a. Sacroilliac Joint

b. Cervical Spine Anatomy

c. Thoracic Spine Anatomy

d. Lumbar Spine Anatomy

e. Degenerative Disc Disease

f. Facet Join Syndromes

g. Opioids

3. Testimonials

i. Discogram

i. Vertebral Discs

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Marcos Szeinfeld Paul Wu Kevin Cairns MD American Pain Experts APEx Nevro Spinal Cord Stimulation Fort Lauderdale Pain  Robert m? Levy  MD Louis Raso MD Holy cross Melanie ROSENBLATT South florida spine  Spine and orthopedic center Boca raton pain management Cleveland clinic pain Mayo clinic pain management Emory university  pain management  Serio lenchig Paul Rao Carlos Casas Ira B Fox Paul Rodriguez pain management  Vertos Vertiflex Bioness

Marcos Szeinfeld

Paul Wu

Kevin Cairns MD

American Pain Experts

APEx

Nevro

Spinal Cord Stimulation

Fort Lauderdale Pain

Robert m? Levy

MD

Louis Raso MD

Holy cross

Melanie ROSENBLATT

South florida spine

Spine and orthopedic center

Boca raton pain management

Cleveland clinic pain

Mayo clinic pain management

Emory university

pain management

Serio lenchig

Paul Rao

Carlos Casas

Ira B Fox

Paul Rodriguez pain management

Vertos

Vertiflex

Bioness

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